Growth hormone GH or somatotropin , also known as human growth hormones hGH or HGH in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. GH is a amino acid , single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. A recombinant form of hGH called somatropin INN is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency.
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Alongside this trend, there has been an explosion in the sales of lightly regulated, under-researched herbal and dietary weight loss supplements. The first global review in 19 years regarding the efficacy of herbal and dietary supplements for weight loss was recently presented by researchers from the University of Sydney USYD in Australia to the European Congress on Obesity ECO. The research, which encompassed two literature reviews including randomized placebo-controlled trials involving over 10, participants with overweight or obesity, found insufficient evidence that herbal and dietary supplements produce clinically significant weight loss. Erica Bessell , lead author of the study, said:.
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In clinical practice, every year approximately , children are referred with short stature SS based on a cut-off of fifth percentile. The lack of reliable data on the prevalence of GHD in India limits estimation of the magnitude of this problem. The diagnosis and treatment of GHD are hurdled with various challenges, restricting the availability of growth hormone GH therapy to only a very limited segment of the children in India.
Background: Human growth hormone GH is widely used as an antiaging therapy, although its use for this purpose has not been approved by the U. Food and Drug Administration and its distribution as an antiaging agent is illegal in the United States. Purpose: To evaluate the safety and efficacy of GH therapy in the healthy elderly. Study selection: The authors included randomized, controlled trials that compared GH therapy with no GH therapy or GH and lifestyle interventions exercise with or without diet with lifestyle interventions alone. The authors excluded studies that evaluated GH as treatment for a specific illness.